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Vandetanib and Bevacizumab in Treating Patients With Advanced Solid Tumors or Lymphoma


ABSTRACT: RATIONALE: Vandetanib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Bevacizumab and vandetanib may also stop the growth of cancer cells by blocking blood flow to the cancer. Giving vandetanib together with bevacizumab may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of vandetanib and bevacizumab in treating patients with advanced solid tumors or lymphoma.

DISEASE(S): Lung Cancer,Lymphoproliferative Disorders,Lymphoproliferative Disorder,Small Intestine Cancer,Angioimmunoblastic T-cell Lymphoma,Lymphoma,Lung Neoplasms,Intestinal Neoplasms,Unspecified Adult Solid Tumor, Protocol Specific

PROVIDER: 2059705 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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