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Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer

ABSTRACT: This phase I trial studies the side effects and best dose of alisertib when given together with irinotecan hydrochloride in treating patients with advanced solid tumors or colorectal cancer. Irinotecan hydrochloride and alisertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

DISEASE(S): Adenocarcinoma,Signet Ring Adenocarcinoma Of The Rectum,Colorectal Cancer,Unspecified Adult Solid Tumor, Protocol Specific,Recurrent Colon Cancer,Rectal Neoplasms,Cystadenocarcinoma,Signet Ring Adenocarcinoma Of The Colon,Colorectal Neoplasms,Adenocarcinoma, Mucinous,Mucinous Adenocarcinoma Of The Colon,Recurrent Rectal Cancer,Colonic Neoplasms,Stage Iiia Colon Cancer,Mucinous Adenocarcinoma Of The Rectum

PROVIDER: 2150139 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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