Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

ABSTRACT: This clinical trial studies personalized dose monitoring of busulfan and combination chemotherapy in treating patients with Hodgkin or non-Hodgkin lymphoma undergoing stem cell transplant. Giving chemotherapy before a stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. After treatment, stem cells are collected from the patient’s peripheral blood or bone marrow and stored. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. Monitoring the dose of busulfan may help doctors deliver the most accurate dose and reduce toxicity in patients undergoing stem cell transplant.

DISEASE(S): Recurrent Childhood Small Noncleaved Cell Lymphoma,Adult Grade Iii Lymphomatoid Granulomatosis,Stage Iiib Mycosis Fungoides/sezary Syndrome,Stage Ib Mycosis Fungoides/sezary Syndrome,Lymphoma, Large-cell, Immunoblastic,Stage Ii Childhood Hodgkin Lymphoma,Stage I Adult Diffuse Small Cleaved Cell Lymphoma,Recurrent Childhood Anaplastic Large Cell Lymphoma,Stage Iva Mycosis Fungoides/sezary Syndrome,Stage Iv Adult Diffuse Mixed Cell Lymphoma,Childhood Burkitt Lymphoma,Stage Iv Adult Immunoblastic Large Cell Lymphoma,Recurrent Grade 1 Follicular Lymphoma,Stage I Small Lymphocytic Lymphoma,Contiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma,Contiguous Stage Ii Marginal Zone Lymphoma,Leukemia, Hairy Cell,Childhood Immunoblastic Large Cell Lymphoma,Stage I Childhood Large Cell Lymphoma,Stage Ivb Mycosis Fungoides/sezary Syndrome,Mycosis Fungoides,Stage Iv Adult Lymphoblastic Lymphoma,Stage Iii Adult Burkitt Lymphoma,Stage I Grade 1 Follicular Lymphoma,Stage Ii Cutaneous T-cell Non-hodgkin Lymphoma,Recurrent Adult Burkitt Lymphoma,Stage I Childhood Small Noncleaved Cell Lymphoma,Leukemia, T-cell,Lymphomatoid Granulomatosis,Lymphoma, T-cell, Peripheral,Stage Iv Childhood Small Noncleaved Cell Lymphoma,Stage I Childhood Hodgkin Lymphoma,Stage Iv Childhood Anaplastic Large Cell Lymphoma,Lymphoma, B-cell, Marginal Zone,Stage Iiia Mycosis Fungoides/sezary Syndrome,Stage I Adult Immunoblastic Large Cell Lymphoma,Stage Iv Childhood Large Cell Lymphoma,Nodal Marginal Zone B-cell Lymphoma,Noncontiguous Stage Ii Grade 3 Follicular Lymphoma,Childhood Diffuse Large Cell Lymphoma,Recurrent Small Lymphocytic Lymphoma,Lymphoma, T-cell, Cutaneous,Stage Iv Adult Burkitt Lymphoma,Contiguous Stage Ii Grade 3 Follicular Lymphoma,Stage I Adult Diffuse Large Cell Lymphoma,Stage Iii Adult T-cell Leukemia/lymphoma,Stage Iii Adult Diffuse Large Cell Lymphoma,Lymphoma, Follicular,Waldenstrom Macroglobulinemia,Stage I Childhood Anaplastic Large Cell Lymphoma,Recurrent Mantle Cell Lymphoma,Stage Iii Cutaneous T-cell Non-hodgkin Lymphoma,Stage Iii Childhood Large Cell Lymphoma,Contiguous Stage Ii Grade 1 Follicular Lymphoma,Leukemia,Hodgkin Disease,Recurrent Adult Hodgkin Lymphoma,Mycoses,Contiguous Stage Ii Adult Diffuse Large Cell Lymphoma,Childhood Grade Iii Lymphomatoid Granulomatosis,Recurrent Adult Lymphoblastic Lymphoma,Recurrent Childhood Large Cell Lymphoma,Leukemia, Large Granular Lymphocytic,Stage Iib Mycosis Fungoides/sezary Syndrome,Contiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma,Testicular Lymphoma,Stage I Grade 3 Follicular Lymphoma,Noncontiguous Stage Ii Mantle Cell Lymphoma,Stage Iv Childhood Lymphoblastic Lymphoma,Contiguous Stage Ii Grade 2 Follicular Lymphoma,Lymphoma, T-cell,Noncontiguous Stage Ii Adult Diffuse Mixed Cell Lymphoma,Stage Iv Grade 3 Follicular Lymphoma,Immunoblastic Lymphadenopathy,Noncontiguous Stage Ii Marginal Zone Lymphoma,Stage Ia Mycosis Fungoides/sezary Syndrome,Stage Ii Childhood Large Cell Lymphoma,Noncontiguous Stage Ii Small Lymphocytic Lymphoma,Recurrent Adult Diffuse Mixed Cell Lymphoma,Stage Iii Childhood Small Noncleaved Cell Lymphoma,Stage Ii Adult Hodgkin Lymphoma,Stage Iv Grade 2 Follicular Lymphoma,Contiguous Stage Ii Small Lymphocytic Lymphoma,Recurrent Adult T-cell Leukemia/lymphoma,Stage Iv Cutaneous T-cell Non-hodgkin Lymphoma,Contiguous Stage Ii Mantle Cell Lymphoma,Noncontiguous Stage Ii Adult Diffuse Large Cell Lymphoma,Stage I Grade 2 Follicular Lymphoma,Lymphoma, Non-hodgkin,Recurrent Adult Diffuse Large Cell Lymphoma,Lymphoma, B-cell,Stage Ii Childhood Anaplastic Large Cell Lymphoma,Stage I Adult T-cell Leukemia/lymphoma,Extranodal Marginal Zone B-cell Lymphoma Of Mucosa-associated Lymphoid Tissue,Lymphoma, Large B-cell, Diffuse,Contiguous Stage Ii Adult Lymphoblastic Lymphoma,Stage Iv Adult T-cell Leukemia/lymphoma,Stage Iv Adult Diffuse Large Cell Lymphoma,Contiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma,Noncontiguous Stage Ii Adult Immunoblastic Large Cell Lymphoma,Small Intestine Lymphoma,Refractory Hairy Cell Leukemia,Sezary Syndrome,T-cell Large Granular Lymphocyte Leukemia,Stage Ii Childhood Small Noncleaved Cell Lymphoma,Adult Nasal Type Extranodal Nk/t-cell Lymphoma,Stage Iii Childhood Anaplastic Large Cell Lymphoma,Splenic Marginal Zone Lymphoma,Stage I Childhood Lymphoblastic Lymphoma,Stage I Marginal Zone Lymphoma,Lymphoma, Mantle-cell,Noncontiguous Stage Ii Adult Burkitt Lymphoma,Leukemia-lymphoma, Adult T-cell,Stage Iii Adult Diffuse Small Cleaved Cell Lymphoma,Recurrent Adult Immunoblastic Large Cell Lymphoma,Stage Iv Grade 1 Follicular Lymphoma,Stage Iv Mantle Cell Lymphoma,Stage I Adult Hodgkin Lymphoma,Recurrent Childhood Lymphoblastic Lymphoma,Stage I Adult Diffuse Mixed Cell Lymphoma,Contiguous Stage Ii Adult Burkitt Lymphoma,Lymphoma, Extranodal Nk-t-cell,Stage Ii Adult T-cell Leukemia/lymphoma,Plasmablastic Lymphoma,Stage I Cutaneous T-cell Non-hodgkin Lymphoma,Burkitt Lymphoma,Stage I Mantle Cell Lymphoma,Stage Iii Childhood Lymphoblastic Lymphoma,Recurrent Adult Diffuse Small Cleaved Cell Lymphoma,Stage Iii Grade 1 Follicular Lymphoma,Stage Iii Adult Immunoblastic Large Cell Lymphoma,Stage Iii Marginal Zone Lymphoma,Stage Iii Adult Diffuse Mixed Cell Lymphoma,Recurrent Marginal Zone Lymphoma,Stage Ii Childhood Lymphoblastic Lymphoma,Recurrent Adult Grade Iii Lymphomatoid Granulomatosis,Leukemia, Lymphocytic, Chronic, B-cell,Intraocular Lymphoma,Stage I Adult Lymphoblastic Lymphoma,Noncontiguous Stage Ii Adult Diffuse Small Cleaved Cell Lymphoma,Recurrent Grade 3 Follicular Lymphoma,Stage Iii Adult Hodgkin Lymphoma,Stage Iii Grade 2 Follicular Lymphoma,Waldenström Macroglobulinemia,Recurrent Childhood Grade Iii Lymphomatoid Granulomatosis,Noncutaneous Extranodal Lymphoma,Angioimmunoblastic T-cell Lymphoma,Stage Iv Marginal Zone Lymphoma,Lymphoma, Large-cell, Anaplastic,Stage Iv Adult Hodgkin Lymphoma,Stage Iii Mantle Cell Lymphoma,Noncontiguous Stage Ii Grade 2 Follicular Lymphoma,Stage Iii Grade 3 Follicular Lymphoma,Hepatosplenic T-cell Lymphoma,Stage Iv Adult Diffuse Small Cleaved Cell Lymphoma,Precursor Cell Lymphoblastic Leukemia-lymphoma,Noncontiguous Stage Ii Grade 1 Follicular Lymphoma,Recurrent Cutaneous T-cell Non-hodgkin Lymphoma,Noncontiguous Stage Ii Adult Lymphoblastic Lymphoma,Stage Iv Small Lymphocytic Lymphoma,Lymphoma,Childhood Nasal Type Extranodal Nk/t-cell Lymphoma,Recurrent Mycosis Fungoides/sezary Syndrome,Stage Iv Childhood Hodgkin Lymphoma,Anaplastic Large Cell Lymphoma,Stage Iii Small Lymphocytic Lymphoma,Recurrent Grade 2 Follicular Lymphoma,Peripheral T-cell Lymphoma,Stage Iii Adult Lymphoblastic Lymphoma,Stage Iia Mycosis Fungoides/sezary Syndrome,Recurrent/refractory Childhood Hodgkin Lymphoma,Cutaneous B-cell Non-hodgkin Lymphoma,Stage Iii Childhood Hodgkin Lymphoma,Stage I Adult Burkitt Lymphoma

PROVIDER: 2152905 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR