Efficiency of transanal irrigation and stimulation of a nerve of the ankle to improve symptoms and quality of life after radical surgery of rectal cancer

ABSTRACT: Background and study aims Rectal cancer (cancer of the rectum) affects the lower part of the colon that connects to the anus. In many patients undergoing surgery to remove rectal cancer (and who have also received radiotherapy) the anus is not removed and patients may continue to defecate through this natural route. However, the removal of all or part of the rectum can cause faecal incontinence (involuntary leakage of faeces), urgency (must urgently seek a toilet), and fragmentation of the stool which forces them to perform small and repeated defecations. There is no specific treatment that improves these symptoms. This study compares the effects of two non-invasive and non-painful procedures for this situation. Transanal irrigation using a mechanical device (Peristeen®) attempts to empty the stool at once, allowing a normal life until the bowel is filled again with faeces. Electrical stimulation through a nerve in the leg (tibial nerve) can be used to improve the sensitivity and strength of the muscles of the pelvis and improve their ability to contain and expel the stool. The aim of this study is to compare the effects of Peristeen and tibial nerve stimulation in patients who have problems with continence and expulsion of feces that affect their quality of life and daily activities. Who can participate? Patients aged 20 to 80 who have been operated on for rectal cancer at least one year before the study What does the study involve? Participants are randomly allocated to be treated with either transanal irrigation using Peristeen® or posterior tibial nerve stimulation. The severity of their symptoms is recorded at the start of the study and after 12, 18 and 24 weeks.

DISEASE(S): Patients Operated For Rectal Cancer With Sphincter Preservation And Poor Postoperative Intestinal Function

PROVIDER: 2413124 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR