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Expression profiling of clonally derived skeletal progenitors from mouse bone marrow

ABSTRACT: Bone marrow stromal cells (BMSCs) were isolated from the femora and tibiae of irtTA-GBD*-TAg transgenic mice. Using cellular cloning we established skeletal progenitors with distinct differentiation properties and analysed their transcriptome. Unipotent osteogenic and adipogenic cells expressed specific transcriptional programs whereas bipotent clones combined expression of those genes and did not show a unique signature.

ORGANISM(S): Mus musculus

PROVIDER: GSE114474 | GEO | 2018/07/02

REPOSITORIES: GEO

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