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The in vitro influence of orexin B on the porcine myometrium on days 15 to 16 of gestation.

ABSTRACT: Orexin A (OXA) and orexin B (OXB) are hypothalamic-derived peptides that participate in the regulation of energy metabolism, food intake and reproductive function by influencing the hypothalamic-pituitary-ovarian axis. Orexins are also produced in the endometrium, myometrium and placenta, which suggests that they could act as a link between energy metabolism and the reproductive system. The aim of this study was to explore the influence of orexin B on global gene expression in the porcine myometrium during early gestation, on days 15 to 16 of pregnancy (implantation period).

ORGANISM(S): Sus scrofa domesticus Sus scrofa

PROVIDER: GSE122414 | GEO | 2018/11/14

REPOSITORIES: GEO

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The in vitro influence of orexin A on the porcine endometrium on days 15 to 16 of gestation.

Project description:Orexin A belongs to the group of hypothalamic-derived peptides that are involved in a number of processes, such as regulation of energy metabolism, control of food intake and regulation of the reproductive system. Orexin A is also expressed in the endometrium, myometrium and placenta, which suggests that it may act as an important local regulator of the reproductive functions. The aim of this study was to explore the influence of orexin A on global gene expression in the porcine endometrium during early gestation, on days 15 to 16 of pregnancy (implantation period).

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The in vitro effect of orexin A on the porcine myometrial transcriptomic profile during early-implantation period

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The in vitro influence of orexin B on the porcine endometrium on days 15 to 16 of gestation.

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