Genome-wide maps of chromatin state in TRIB3-shRNA and control lymphoma cells
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ABSTRACT: We report the application of single-molecule-based sequencing technology for high-throughput profiling of RNAPII with promoters in mammalian cells. We performed ChIP sequencing with antibody to total RNAPII in TRIB3-cas9 and control group. Inspection of multiple individual traces and global analyses showed that TRIB3 deletion globally reduced association of RNAPII with promoters.
ORGANISM(S): Homo sapiens
PROVIDER: GSE126743 | GEO | 2020/10/02
REPOSITORIES: GEO
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