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Genome-wide maps of chromatin state in ad-ube3b or Pep2-CM4-treated and control lymphoma cells

ABSTRACT: We report the application of single-molecule-based sequencing technology for high-throughput profiling of RNAPII with promoters in mammalian cells. We performed ChIP sequencing with antibody to total RNAPII in UBE3B overexpression or Pep2-CM4-treated and control group. Inspection of multiple individual traces and global analyses showed that UBE3B overexpression globally reduced association of RNAPII with promoters.

ORGANISM(S): Homo sapiens

PROVIDER: GSE126745 | GEO | 2020/10/02

REPOSITORIES: GEO

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