Methylation profiling

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DNA methylation profiling of paired parental and therapy resistant cancer cell lines


ABSTRACT: Genome wide DNA methylation profiling of paired parental and therapy resistant cancer cell lines. Parental cell lines are mostly established cell lines. Resistant cell lines were obtained through long term exposure of the parental cells to gradually increasing doses of cancer therapies. The Illumina Infinium 450k and EPIC Human DNA methylation Beadchips were used to obtain DNA methylation profiles across approximately 450,000 or 850,000 CpGs from the cells. Samples include 7 parental and 10 derived resistant cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE128684 | GEO | 2020/02/20

REPOSITORIES: GEO

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