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Cognate T cell interactions affect the DC transcriptome [dataset 4]

ABSTRACT: Our data suggest that peptide-presenting DC receive signals from synapse-forming antigen specific CD4+ or CD8+ T cells that alter the DC expression profile. To further test this notion, we hock immunized T cell-engrafted mice with NP harboring CpG and coated with OVA (OVA / CpG NP) or the control antigen BSA (BSA / CpG NP) and isolated NP+ DC for RNAseq.

ORGANISM(S): Mus musculus

PROVIDER: GSE129214 | GEO | 2019/04/03

REPOSITORIES: GEO

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