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An RNA Polymerase Ribozyme that Synthesizes its Own Ancestor

ABSTRACT: As part of an examination of a newly-evolved RNA polymerase ribozyme, 38-6, products of primer extension experiments using an RNA template encoding the hammerhead RNA endonuclease ribozyme, using 38-6 and its less active ancestor 24-3. These products were analyzed by next-generation sequencing to determine the rates of substitution, deletion, and insertion mutations for both polymerases.

ORGANISM(S): synthetic construct

PROVIDER: GSE142114 | GEO | 2019/12/17

REPOSITORIES: GEO

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