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RNAseq measurement of cortisol induced gene expression change under knockout of Klf9

ABSTRACT: We found that a frameshift deletion introduced into exon 1 of zebrafish klf9 eliminates the DNA binding domain and significantly reduces expression of the mature transcript. RNA-seq shows that klf9 is required for the pro-inflammatory transcriptomic effects of chronic cortisol treatment. klf9 is one of a core set of genes consistently found to be upregulated by chronic cortisol exposure.

ORGANISM(S): Danio rerio

PROVIDER: GSE144885 | GEO | 2020/07/15

REPOSITORIES: GEO

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RNAseq measurement of cortisol induced gene expression change under knockout of Klf9

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