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Expression data of sham and p21-overexpressed MLE-12 cells

ABSTRACT: We report that p21 expression was increased in the alveolar epithelial type 2 cells (AEC2s) in a time dependent manner following multiple bleomycin induced pulmonary fibrosis (PF). The AEC2s with the elevated expression of p21 exhibited cell senescence and lost the ability of self-renewal and differentiation. Evaluation of mRNA profiles in sham and p21-adenovirus treated MLE-12 cells is helpful to analyze the changes of lung alveolar epithelial cells after p21 deposition.

ORGANISM(S): Mus musculus

PROVIDER: GSE166198 | GEO | 2022/02/01

REPOSITORIES: GEO

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Expression data of sham and p21-overexpressed MLE-12 cells

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