Transcriptomics

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Gene expression data from S. aureus-exposed neutrophils


ABSTRACT: Neutrophil lysis after phagocytosis is a process potentially important in the pathogenesis of community-associated methicillin-resistant S. aureus (CA-MRSA) infection. The mechanism for this process is not currently known. Therefore, to better understand CA-MRSA virulence we used human oligonucleotide microarrays to investigate the mechanism underlying enhanced PMN lysis that occurs after phagocytosis of CA-MRSA. In order to examine the effect of S. aureus on the neutrophil transcriptome and to elucidate any possible differences in this effect between hospital- and community-associated S. aureus, we performed microarray expression analysis on human neutrophils treated with hospital- and community-associated S. aureus.

ORGANISM(S): Homo sapiens

PROVIDER: GSE16837 | GEO | 2010/06/01

SECONDARY ACCESSION(S): PRJNA117601

REPOSITORIES: GEO

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