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RNA-Seq of CD8+ T cell subsets during LCMV infection [RNA-seq_D5_JQ1]

ABSTRACT: P14 cells were transferred to naïve mice subsequently infected with LCMV. Mice were treated with JQ1 or vehicle on days 1-4 of infection. On day 5 of infection KLRG1loCD127lo EEC were sorted for RNAseq analysis. In a separate experiment, P14 cells were transduced with shBrd4a or shBrd4b and mixed with shCtrl transduced P14 cells, and then transferred into naïve mice subsequently infected with LCMV. On day 5 post-infection, transduced EEC were sorted for RNAseq.

ORGANISM(S): Mus musculus

PROVIDER: GSE173510 | GEO | 2021/05/21

REPOSITORIES: GEO

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miRNA signatures of antigen specific CD8+ T cells at different stages of immune response to LCMV infection

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