Transcriptomics

Dataset Information

0

Expression profiles of E4BP4 knockout RAW264.7 cells [RAW_KOvsWT_RNA-seq]


ABSTRACT: Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to evaluate the gene expression of E4BP4 knockout (KO) RAW264.7 cells. Methods: We generated E4BP4-KO RAW264.7 Cell Line using CRISPR-CAS9 system. Control plasmid was encoding the Cas9 nuclease without gRNA sequence. Total RNA of E4BP4-KO and Control (CTRL) RAW264.7 cells was extracted. RAW264.7 cells RNA profiles were generated by deep sequencing for two groups (E4BP4-KO versus CTRL RAW264.7 cells) with three samples each. Results: There were significant differences between E4BP4-KO and CTRL RAW264.7 cells. Conclusions: Deletion of E4BP4 in RAW264.7 cells induced various changes at the transcription level.

ORGANISM(S): Mus musculus

PROVIDER: GSE183076 | GEO | 2024/03/31

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-03-31 | GSE233929 | GEO
2024-03-31 | GSE233928 | GEO
2021-01-19 | GSE121387 | GEO
2024-03-31 | GSE183079 | GEO
2014-03-21 | E-GEOD-55014 | biostudies-arrayexpress
2021-05-01 | GSE150988 | GEO
2024-03-31 | GSE183529 | GEO
| PRJNA635395 | ENA
2014-03-21 | GSE55014 | GEO
2024-03-31 | GSE183078 | GEO