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The role of NLRP3 in intra-amniotic inflammation-induced preterm birth

ABSTRACT: Macrophages and neutrophils were sorted from the decidua and uterus of Nlrp3+/+ and Nlrp3-/- mice injected with lipopolysaccharide (LPS) or PBS and analyzed using pair-end RNA-sequencing (RNA-seq) to evaluate the effect of Nlrp3 deficiency on the transcriptomes of these innate immune cells in preterm birth.

ORGANISM(S): Mus musculus

PROVIDER: GSE183698 | GEO | 2021/12/01

REPOSITORIES: GEO

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The role of NLRP3 in intra-amniotic inflammation-induced preterm birth

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