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A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B

ABSTRACT: Decidual and uterine macrophages as well as neutrophils from Nlrp3+/+ and Nlrp3-/- mice injected with S100B or PBS were sorted and analyzed using pair-end BGI RNA sequencing (RNA-seq) to evaluate the effect of Nlrp3 deficiency on the transcriptome of these innate immune cells in preterm birth.

ORGANISM(S): Mus musculus

PROVIDER: GSE217041 | GEO | 2023/06/20

REPOSITORIES: GEO

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The role of NLRP3 in intra-amniotic inflammation-induced preterm birth

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