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GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

ABSTRACT: Glucose is critical to the development, homeostasis, and survival of nucleus pulposus cells. GLUT1 is a major glucose transporter, a NP phenotypic cell marker, and highly expressed in nucleus pulposus (NP) cells, however its level of importance in NP cell development and homeostasis is unknown. We used microarrays to explore the transcriptomics of differentially expressed genes between wildtype and Glut1 cKO NP cells in 9-month-old mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE208396 | GEO | 2023/06/30

REPOSITORIES: GEO

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GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

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