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Extrahepatic tumors induce inflammation causing liver depletion of HNF4a and driving a systemic metabolic rewiring

ABSTRACT: To evaluate whether liver metabolic pathways are affected by non-hepatic cancer in-vivo, we performed RNA sequencing of hepatocytes isolated from perfused livers of WT and 4T1 breast cancer-bearing mice on days 4 and 21 following cancer cells injection.

ORGANISM(S): Mus musculus

PROVIDER: GSE212113 | GEO | 2023/03/27

REPOSITORIES: GEO

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Extrahepatic tumors induce inflammation causing liver depletion of HNF4a and driving a systemic metabolic rewiring II

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