RNA sequencing of human peripheral blood cDC1 treated with PGE2
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ABSTRACT: RNA sequencing was used to characterize PGE2-mediated changes in the gene expression profile of human conventional type 1 dendritic cells (cDC1) purified from PBMCs of healthy donors. Our analysis shows that treatment of cDC1 with PGE2 induces transcriptional changes in resting cDC1. cDC1 activated with a TLR3 ligand after PGE2 pre-treatment show alterations in the expression of activation induced genes.
ORGANISM(S): Homo sapiens
PROVIDER: GSE213691 | GEO | 2023/05/27
REPOSITORIES: GEO
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