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RNA sequencing of murine bone marrow cell-derived cDC1 treated with PGE2

ABSTRACT: RNA sequencing was used to characterize PGE2-mediated changes in the gene expression profile of conventional type 1 dendritic cells (cDC1). Our analysis shows that treatment of cDC1 with PGE2 or conditioned medium from PGE2-producing tumors induces transcriptional changes in resting cDC1. cDC1 activated with a TLR3 ligand after PGE2 pre-treatment show alterations in the expression of activation induced genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE213205 | GEO | 2023/05/27

REPOSITORIES: GEO

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