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The mRNA levels of CD133 positive and CD133 negative cells after radiation exposure

ABSTRACT: The cancer initiating cells (CICs) act as a tumor initiation source. Recent studies have shown that CICs contribute to chemoresistance and radioresistance. The aims of this study were to investigate the relationship of CD133+ liver CICs and radiation resistance and to define a possible mechanism for radioresistance in hepatocellular carcinoma (HCC).

ORGANISM(S): Homo sapiens

PROVIDER: GSE22247 | GEO | 2013/07/20

SECONDARY ACCESSION(S): PRJNA128761

REPOSITORIES: GEO

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The mRNA levels of CD133 positive and CD133 negative cells after radiation exposure

Project description:The cancer initiating cells (CICs) act as a tumor initiation source. Recent studies have shown that CICs contribute to chemoresistance and radioresistance. The aims of this study were to investigate the relationship of CD133+ liver CICs and radiation resistance and to define a possible mechanism for radioresistance in hepatocellular carcinoma (HCC). Total RNA is obtained from CD133 positive cells and CD133 negative cells at 0, 12 and 24 hours after radiation exposure.

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