Transcriptomics

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Gene expression profiling of shCtrl and shCNN2 RKO cells from Clariom S array.


ABSTRACT: CNN2 is identified as a tumor promotor in the development of colorectal cancer. Herein, gene expression in RKO cells infected with shCtrl and shCNN2 (for CNN2 knockdown) was detected with a Clariom S array. Gene expression profiling of shCtrl and shCNN2 RKO cells was acquired and analyzed. Differentially expressed genes were identified based on fold change of mean of expression (fold change ≥ 1.3) and FDR (< 0.05) from P value calculated based on linear model of empirical Bayesian distribution. In total, 523 upregulated genes and 648 downregulated genes were characterized.

ORGANISM(S): Homo sapiens

PROVIDER: GSE229716 | GEO | 2023/05/04

REPOSITORIES: GEO

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