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DNA methylation changes in mice induced by mock parabiosis

ABSTRACT: Aging is classically conceptualized as an ever-increasing trajectory of damage accumulation and loss of function, leading to increases in morbidity and mortality. However, recent in vitro studies have raised the possibility of age reversal. We characterized several models in which biological age, assessed primarily through analysis of DNA methylation, undergoes reversible changes. Heterochronic parabiosis is one such example.

ORGANISM(S): Mus musculus Homo sapiens Macaca mulatta Rattus

PROVIDER: GSE236617 | GEO | 2023/07/06

REPOSITORIES: GEO

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