Characterizing Local Extension of Retinoblastoma by Single-cell Transcriptomics
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ABSTRACT: Retinoblastoma (RB) is the most prevalent ocular tumor of childhood whose extraocular invasion largely increase metastasis risk. Nevertheless, a single-cell characterization of RB local extension has been lacking. Here, we perform single-cell RNA sequencing (scRNA-seq) 4 RB samples (2 from intraocular and 2 from extraocular RB patients), and integrate public scRNA-seq datasets to characterize the local extension of RB at single-cell level.
ORGANISM(S): Homo sapiens
PROVIDER: GSE249995 | GEO | 2023/12/19
REPOSITORIES: GEO
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