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High-throughput exploration of single-cell transcriptional alterations associated with remote fear memory formation

ABSTRACT: Leveraging SPEED in tandem with snRNA-Seq, we uncover molecular identities of distinct neural subtypes, concurrent 5hmC alterations at active enhancers and gene bodies, and dynamic gene expression associated with remote memory formation. This comprehensive analysis encompasses several thousand cells from the cerebral and cerebellar cortex of home-caged (HC) and fear-conditioned (FC) mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE254380 | GEO | 2025/01/01

REPOSITORIES: GEO

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