Expression profiling of 4q-linked and phenotypic FSHD in different steps of myogenic differentiation
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ABSTRACT: The specific gene(s) responsible for FSHD phenotype have not yet been identified. We used the Human GeneChip Exon 1.0 ST platform to analyze the global gene expression profiles of FSHD-1, FSHD-2 and controls during myogenic differentiation. In this dataset, we include the expression data of human primary myoblasts obtained from three FSHD-1 and two FSHD-2 patients, and three healthy controls (CN). This data are used to evaluate the molecular perturbation of FSHD upon muscle differentiation; we compared patients and CN proliferating myoblasts as well as the corresponding myotubes obtained after 8 days of cell differentiation.
ORGANISM(S): Homo sapiens
PROVIDER: GSE26061 | GEO | 2011/07/07
SECONDARY ACCESSION(S): PRJNA135571
REPOSITORIES: GEO
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