Methylation profiling

Dataset Information

0

Lineage-specific genomic imprinting in the ZNF791 locus [BiSulfite-seq]


ABSTRACT: To identify genomic imprinting in pigs, we generated parthenogenetic porcine embryos alongside biparental normal embryos, and then performed whole-genome bisulfite sequencing and RNA sequencing on these samples. In our analyses, we discovered a maternally methylated differentially methylated region within the orthologous ZNF791 locus in pigs, while identifying both a major imprinted isoform of the ZNF791-like gene and an imprinted antisense transcript that has not been previously annotated. Importantly, our comparative analyses of the orthologous ZNF791 gene in various eutherian mammals, including humans, non-human primates, rodents, artiodactyls, and dogs, revealed that this gene is subjected to genomic imprinting exclusively in domesticated animals, thereby highlighting lineage-specific imprinting.

ORGANISM(S): Sus scrofa

PROVIDER: GSE263495 | GEO | 2024/10/16

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-10-16 | GSE263494 | GEO
2023-03-04 | GSE218486 | GEO
2023-03-04 | GSE218485 | GEO
2009-02-06 | GSE10443 | GEO
2010-05-06 | E-GEOD-10443 | biostudies-arrayexpress
2010-05-05 | GSE18126 | GEO
2010-05-04 | E-GEOD-18126 | biostudies-arrayexpress
2016-06-01 | E-GEOD-64244 | biostudies-arrayexpress
2021-02-22 | GSE146202 | GEO
2010-07-07 | E-GEOD-17964 | biostudies-arrayexpress