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A DNA methylation database of human and mouse hematological malignancy cell lines

ABSTRACT: Human cancer cell lines constitute useful models to model the primary disease and many relevant findings in tumor biology have been originated from them since the first immortalized cell line (HeLa) was obtained. The easy experimental intervention, the purity of the transformed cells and their versatility to undergo high-throughput screenings represent advantageous features of the established cancer cell lines. Herein, we have obtained the DNA methylation profiles of 210 cell lines derived from hematological malignancies utilizing comprehensive DNA methylation microarrays that interrogate more than 850,000 and 285,000 CpG sites from human and mouse genomes, respectively.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE270494 | GEO | 2024/11/05

REPOSITORIES: GEO

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