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Effect of depletion of SIRT6 in gene expression in Nucleus pulposus cells

ABSTRACT: SIRT6 is a well known histone deactylase enzyme. Here, we report the effect of its depletion in nucleus pulposus cells from rattus norvegicus. RNA seq was performed on control and sirt6 depelted cells via lentiviral transfection method. Downstream analysis includes upregulated and downregulated signalling molecules with respect to SIRT6 depletion.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE276440 | GEO | 2024/10/02

REPOSITORIES: GEO

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