Transcriptomics

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Response of Saccharomyces cerevisiae to a rapid transfer from a fermentable to a nonfermentable carbon source.


ABSTRACT: The global gene expression program that accompanies the adaptation of Saccharomyces cerevisiae to an abrupt transfer from a fermentable to a nonfermentable carbon source was characterized by using a cDNA microarray to monitor the relative abundances and polysomal distributions of mRNAs. Features of the program included a transient reduction in global translational activity and a severe decrease in polysome size of transcripts encoding ribosomal proteins. A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments. Keywords: replicate_design

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE3190 | GEO | 2005/08/25

SECONDARY ACCESSION(S): PRJNA92845

REPOSITORIES: GEO

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