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MRNA profiling of LNCaP cells treated with miR-31

ABSTRACT: To determine the altered microRNA expression signature in human prostate cancer compared to benign prostate tissue. To determine the altered mRNA expression signatures upon overexrpession miR-31 in prostate cancer cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36801 | GEO | 2013/02/05

SECONDARY ACCESSION(S): PRJNA156857

REPOSITORIES: GEO

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mRNA profiling of LNCaP cells treated with miR-31

Project description:To determine the altered microRNA expression signature in human prostate cancer compared to benign prostate tissue. To determine the altered mRNA expression signatures upon overexrpession miR-31 in prostate cancer cells. Two condition experiments:1) Total RNA from 21 pairs of prostate cancers and matched benign prostate tissues were collected and processed for microRNA detection. 2) In LNCaP prostate cancer cells, miR-31 was overexpressed and compared to control miR-NC.

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