Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Global gene expression analysis of fibroblast, dOB, osteoblast, MSC and MSC-OB

ABSTRACT: Comparison of each cell mRNA expression pattern. We generated osteoblasts like cell by direct reprogramming technique from human fibroblast. To confirm dOB gene expression pattern similarity to osteoblasts, we analyzed and compared the gene expression profiles of the samples by cDNA microarry. These analysis revealed that dOB are similar to osteoblats in comparative level to MSC-OB.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52817 | GEO | 2015/05/08

SECONDARY ACCESSION(S): PRJNA230130

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Global gene expression analysis of fibroblast, dOB, osteoblast, MSC and MSC-OB

Project description:Comparison of each cell mRNA expression pattern. We generated osteoblasts like cell by direct reprogramming technique from human fibroblast. To confirm dOB gene expression pattern similarity to osteoblasts, we analyzed and compared the gene expression profiles of the samples by cDNA microarry. These analysis revealed that dOB are similar to osteoblats in comparative level to MSC-OB. 6 samples.

2015-05-08 | E-GEOD-52817 | biostudies-arrayexpress

Global gene expression analysis of HDF, HDF OBM, CiOB, MSC-OBs, pOBs

Project description:Comparason of each cell mRNA expression pattern We induced osteoblastic nature in human fibroblast using small compounds. To confirm CiOB gene expression pattern similarity to mesenchymals stem cells derived osteoblasts and primary osteoblasts, we analyzed and compared the gene expression profiles of the samples by cDNA microarry. The analysis revealed that CiOB are similar to osteoblasts.

2018-06-06 | GSE101140 | GEO

Gene expression analysis of mesenchymal stem cells (MSC), osteoblasts and the U2OS (osteosarcoma) cell line

Project description:Transcriptional profiling of MSC, Osteoblasts and U2OS cells. The aim was to quantitate relative gene expression in MSC, osteoblasts and U2OS. MSC and osteoblasts were used as normal cells in this study because osteosarcoma most likely originates from MSC or osteoblasts.

2012-03-02 | GSE27900 | GEO

Genes differentially expressed during early osteoblast (OB) differentiation

Project description:RNA-seq analysis was performed to identify early OB-regulating genes in C3H10T1/2 MSCs.

2021-03-20 | GSE169224 | GEO

Gene expression in the GWAT of ob/ob and ob/ob/Fsp27-/- mice

Project description:GWAT store most of the TAG in mice, ob/ob mice is an obese mice. Ob/ob/Fsp27-/- mice are lean when compared with ob/ob mice. The GWAT weight was dramatically reduced in ob/ob/Fsp27-/- mice. We next extract the total RNA from the GWAT of ob/ob and ob/ob/Fsp27-/- mice, to perform microaary analysis using Mouse Genome 430 2.0 arrays, Affymetrix. We then analysised the up-regulated and down regulated pathways.

2015-04-17 | GSE59807 | GEO

Gene expression in the GWAT of ob/ob and ob/ob/Fsp27-/- mice

2015-04-17 | E-GEOD-59807 | biostudies-arrayexpress

Gene Expression in the BAT and WAT of ob/ob and ob/ob/Cidea-/-/Cidec-/- mice

Project description:ob/ob mice is an obese mice. CIDE family proteins including Cidea, Cideb and Cidec play important role in lipid metabolism. Cidea is mainly expressed in the brown adipose tissue (BAT). Cidec is mainly expressed in the BAT and white adipose tissue (WAT). We generated ob/ob/Cidea-/-/Cidec-/- mice to investigate the phenotype of fat tissue. ob/ob/Cidea-/-/Cidec-/- mice are lean when compared with ob/ob mice. The tissue weight and TAG content of BAT and WAT was extreamly decreased in ob/ob/Cidea-/-/Cidec-/- mice compared with that in ob/ob mice. We next extract the total RNA from the BAT and WAT of ob/ob and ob/ob/Cidea-/-/Cidec-/- mice, to perform microarray analysis using Mouse Gene 1.0 ST array system, Affymetrix. We then analysised the up-regulated and down regulated pathways.

2018-04-18 | GSE100989 | GEO