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Transcriptional response to stress in serum deprived mouse fibroblasts

ABSTRACT: We have employed gene expression profiling in order to identify targets of transcriptional response to stress in mouse Swiss 3T3 fibroblasts, where we induced p38/MAP kinase pathway using anisomycin.

ORGANISM(S): Mus musculus

PROVIDER: GSE55554 | GEO | 2014/08/12

SECONDARY ACCESSION(S): PRJNA239956

REPOSITORIES: GEO

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Project description:We have employed gene expression profiling in order to identify targets of transcriptional response to stress in mouse Swiss 3T3 fibroblasts, where we induced p38/MAP kinase pathway using anisomycin. Serum starved (72 h) mouse 3T3 cells were treated with anisomycin (188.5 nM) for 1, 3, and 6 h (in triplicates). Untreated, serum-starved cells were used as a control. RNA was collected and gene expression profiling using mouse Agilent expression array (4x44k) was performed.

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