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Development of gene expression signatures for ANP in HUVEC

ABSTRACT: Analysis of HUVEC treated with ANP. ANP is a cardiac hormone, binding to the guanylate cyclase-A (GC-A) receptor with a major role in cardiovascular homeostatic mechanisms. Results provide insight into the molecular mechanisms of ANP in vascular endothelial cell.

ORGANISM(S): Homo sapiens

PROVIDER: GSE56976 | GEO | 2014/04/23

SECONDARY ACCESSION(S): PRJNA245105

REPOSITORIES: GEO

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Development of gene expression signatures for ANP in HUVEC

Project description:Analysis of HUVEC treated with ANP. ANP is a cardiac hormone, binding to the guanylate cyclase-A (GC-A) receptor with a major role in cardiovascular homeostatic mechanisms. Results provide insight into the molecular mechanisms of ANP in vascular endothelial cell. ANP induced gene expression in HUVEC was measured at 0, 1 and 6 hours. Four independent experiments were performed at each time (0, 1 or 6 hours) for each experiment.

2014-04-23 | E-GEOD-56976 | biostudies-arrayexpress

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Cardiac specific deletion of natriuretic peptide receptor A induces different myocardial expression of circular RNA and mRNA involved with metabolism in mice

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Transcription profiling of human HUVEC cells exposed to 250 uM DETA-NONOate for 4 hours in the presence and absence of 10 uM of the guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo-[4,3,2]quinoxalin-1-one (ODQ)

Project description:HUVECs were exposed to 250 uM DETA-NONOate for 4 hours in the presence and absence of 10 uM of the guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo-[4,3,2]quinoxalin-1-one (ODQ). Control cells were exposed to vehicle (methanol 0.1%).

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Phosphatidic acid governs natural egress in Toxoplasma gondii via a guanylate cyclase receptor platform

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Influence of plasma from normal and preeclamptic women on HUVEC cells

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2013-06-30 | E-GEOD-41681 | biostudies-arrayexpress

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