Genomics

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MicroRNAs maintain bivalency in mouse embryonic stem cells [ChIP-seq]


ABSTRACT: The protein Dicer is required for microRNA (miRNA) biogenesis, and therefore Dicer-deficient cells lack all mature, functional miRNAs. Here we investigated the binding of the PRC2 component Ezh2 in wildtype and Dicer-deficient mouse embryonic stem cells genomewide using ChIP-sequencing analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE60160 | GEO | 2016/06/02

SECONDARY ACCESSION(S): PRJNA257650

REPOSITORIES: GEO

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