Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

PHGR1 knockdown in the colorectal cell line HT29

ABSTRACT: HT29 cells were transfected with two different PHGR1-targeted siRNA and a scramble siRNA (control) in four copies. Global mRNA profiling was performed by hybridization to Illumina Human-6 Express BeadChips (version 2). Genes significantly up- or downregulated for both PHGR1-targeted siRNAs were identified.

ORGANISM(S): Homo sapiens

PROVIDER: GSE70053 | GEO | 2016/10/01

SECONDARY ACCESSION(S): PRJNA287540

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

HT29 colon cancer cells: siRNA targeted gene knockdowns vs scrambled siRNA control or GFP siRNA control

Project description:Transcriptional profiling of HT29 colon cancer cells comparing siRNA-targeted knockdowns of glutaminase (GLUT), cytokeratin 20 (KER), DEAD/H box polypeptide 32 (DEAD), ribosomal protein L32 (RPL32) and transcription factor DP1 (TFDP1) versus scrambled siRNA control and GFP siRNA control Keywords: two-color spotted cDNA microarray, siRNA-targeted gene knockdowns

2008-06-21 | GSE11848 | GEO

PARK2 knockdown in 2 glioma cell lines

Project description:The PARK2 gene was knocked down using 2 independent siRNAs in SNB19 and SF539 cell lines A non-targeted scramble siRNA was used as the control.

2014-04-11 | GSE50864 | GEO

FAT1 knockdown in immortalized astrocyte and glioma cell lines

2013-01-10 | GSE40583 | GEO

PARK2 knockdown in 2 glioma cell lines

Project description:The PARK2 gene was knocked down using 2 independent siRNAs in SNB19 and SF539 cell lines A non-targeted scramble siRNA was used as the control. Scramble, PARK2 siRNA#1 or PARK2 siRNA#2 was transfected into each cell line, in duplicate, and RNA analyzed using the Affymetrix U133A 2.0 platform.

2014-04-11 | E-GEOD-50864 | biostudies-arrayexpress

FAT1 knockdown in immortalized astrocyte and glioma cell lines

Project description:The FAT1 gene was knocked down using 2 independent siRNAs, in immortalized human astrocytes and U87 and U251 glioma cell lines. A non-targeted scramble siRNA was used as a control. Scramble, FAT1 siRNA#1 and FAT1 siRNA#2 were transfected into each cell line, in duplicate, and RNA analyzed using the Affymetrix U133A 2.0 platform.

2013-01-10 | E-GEOD-40583 | biostudies-arrayexpress

RNA-seq analysis of differentially expressed genes between WT and siALDOA HT29 cells.

Project description:To investigate the biological function ALDOA in the colorectal cancer, we established HT29 cell lines in which the ALDOA gene has been knocked down by the small interfering RNA (siRNA) technique. We used a siRNA targeting ALDOA (KD) to knockdown ALDOA expression in HT29 cells. A scrambled siRNA (NC) was used as a control. Then RNA-Seq experiment was performed by Novogene Co., Ltd. (Beijing, China) to analyze gene expression changes in HT29 cells. For each sample, three independent biological replicates were performed.

2024-09-23 | GSE277845 | GEO

Identification of Liver Receptor Homologue-1 (LRH-1)-regulated genes in HT29 colorectal cancer cells

Project description:Liver receptor homologue 1 (LRH-1) is an orphan nuclear receptor which has been implicated in the growth and development of breast, pancreatic and colorectal cancers (CRC). In order to identify novel LRH-1-regulated genes in CRC cells, we performed gene expression profiling following siRNA-mediated LRH-1 silencing in the CRC cell line HT29.

2015-10-01 | GSE65814 | GEO

RNA sequencing on HT29 colorectal cancer cell line

Project description:We report the single cell RNA sequencing on HT29 colorectal cancer line with 100 nM dasatinib treatment after double thymidine block.

2020-09-30 | GSE128416 | GEO

Colon cancer HT29 cells: siHX transfected vs. control

Project description:HT29 cells were transsfected with siRNA (siHX), which is targeting the human endogeous retrovirus HERV-HX. Cells were harvested 72 h after transfection and knock-down of HERV-HX was evaluated by quantitative RT-PCR. Keywords: Genetic modification

2009-01-01 | GSE14257 | GEO