Transcriptomics,Multiomics

Dataset Information

0

Tbet regulates the transcriptional programming of Be1 B cells.


ABSTRACT: To investigate the role of Tbet in B cell differentiation to "effector-like" antibody secreting cells (ASC's) we utilized an ex vivo culture system to differentiate B cells (Be1 cells) in the presence of Th1 polarized T cells. To determine the role of Tbet in Be1 cell differentiation we performed RNA-seq on Wt Be1 and Tbet negative (TbetNeg) Be1 cells.  Collectively, these data show that T-bet serves as master regulator for the Be1 cell fate and is required for induction of genes required for ASC differentiation in Be1 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE83697 | GEO | 2019/04/29

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-04-29 | GSE118984 | GEO
2019-05-22 | GSE84948 | GEO
| PRJNA487609 | ENA
2016-08-01 | E-GEOD-81189 | biostudies-arrayexpress
2019-05-17 | GSE95282 | GEO
| PRJNA706657 | ENA
2022-01-27 | GSE150139 | GEO
2022-01-27 | GSE192765 | GEO
2016-08-01 | GSE81189 | GEO
2021-05-10 | GSE168240 | GEO