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ChIP-seq analysis of Rad21 binding during genome activation

ABSTRACT: The formation of a transcriptional competent zygote is a not fully understood process potentially involving changes in chromatin structure. Cohesin and CTCF are important nuclear architectural proteins that contribute to chromatin structure and gene regulation. Here we analyze the genome-wide location of Rad21 binding during zebrafish embryogenesis and show increased Rad21 binding over developmental time (2.5 hpf, 4.5 hpf , 10 hpf).

ORGANISM(S): Danio rerio

PROVIDER: GSE84600 | GEO | 2017/12/01

SECONDARY ACCESSION(S): PRJNA330617

REPOSITORIES: GEO

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Rad21 is the core subunit of cohesin complex in directing genome organization

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