Transcriptomics

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Short RNA profiling of ES cells with and without Dicer


ABSTRACT: To better understand Dicer function, and the potential mechanisms by which RNAi contributes to pluripotency, short RNA expression was profiled from 4 ES cell libraries: 2 made from a Dicer-conditional ES cell line before and several months after deletion of Dicer, and 2 made before and 5 days after demethylation of J1 ES cells with 5-aza-deoxycytidine. Contributed here are the unannotated sequence data from each library, including those sequences that did not match the mouse genome or any known non-coding RNAs. Keywords: 454 sequencing, miRNA, dicer, demethylation

ORGANISM(S): Mus musculus

PROVIDER: GSE9306 | GEO | 2007/10/31

SECONDARY ACCESSION(S): PRJNA102957

REPOSITORIES: GEO

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