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Human lung adenocarcinoma tissue LC-MS/MS

ABSTRACT: This project is a report of a chromosome-based human proteome project focused on chromosome 9 (Chr 9). To reveal missing proteins and undiscovered features in proteomes, LC-MS/MS analysis based identification and characterization were conducted on 5 pairs of lung adenocarcinoma tumors and adjacent non-tumor tissues.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr Je-Yoel Cho

PROVIDER: MSV000079961 | MassIVE | Wed Jul 20 16:45:00 BST 2016

SECONDARY ACCESSION(S): PXD002523

REPOSITORIES: MassIVE

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Publications

Proteogenomic Study beyond Chromosome 9: New Insight into Expressed Variant Proteome and Transcriptome in Human Lung Adenocarcinoma Tissues.

Kim Yong-In YI Lee Jongan J Choi Young-Jin YJ Seo Jawon J Park Jisook J Lee Soo-Youn SY Cho Je-Yoel JY

Journal of proteome research 20151119 12

This is a report of a human proteome project (HPP) related to chromosome 9 (Chr 9). To reveal missing proteins and undiscovered features in proteogenomes, both LC-MS/MS analysis and next-generation RNA sequencing (RNA-seq)-based identification and characterization were conducted on five pairs of lung adenocarcinoma tumors and adjacent nontumor tissues. Before our previous Chromosome-Centric Human Proteome Project (C-HPP) special issue, there were 170 remaining missing proteins on Chr 9 (neXtProt ...[more]

PMID: 26584007

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