Proteomics

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Profiling Endogenous SUMO and Ub Modifications Side-by-Side under Native Conditions


ABSTRACT: Datasets of the proteome-wide profiling of native SUMO post-translational modifications in HCT and HELA cells using a novel method to isolate modified peptides through a diglycyl lysine remnant, as previously used for proteome-wide ubiquitin profiling. Includes ID experiments for the identification of SUMO modification sites, quantification of the effects of proteome inhibition by MG132 using K8 SILAC methods, and side-by-side identification of ubiquitin and sumoylation modification sites.

INSTRUMENT(S): LTQ Orbitrap Velos, Orbitrap Fusion, LTQ Orbitrap Elite, Q Exactive

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090)

SUBMITTER: Elizabeth Komives  

PROVIDER: MSV000081018 | MassIVE | Thu Apr 27 09:04:00 BST 2017

SECONDARY ACCESSION(S): PXD006398

REPOSITORIES: MassIVE

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