Dataset Information
Degradation of Quaternary amine in methanogen
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap XL
ORGANISM(S): Methanolobus Vulcani (ncbitaxon:38026)
SUBMITTER: 
XIN WANG Donald J. Ferguson
PROVIDER: MSV000084013 | MassIVE | Wed Jun 26 11:04:00 BST 2019
SECONDARY ACCESSION(S): PXD014403
REPOSITORIES: MassIVE
Publications
Examination of the Glycine Betaine-Dependent Methylotrophic Methanogenesis Pathway: Insights Into Anaerobic Quaternary Amine Methylotrophy.
Frontiers in microbiology 20191107
Recent studies indicate that environmentally abundant quaternary amines (QAs) are a primary source for methanogenesis, yet the catabolic enzymes are unknown. We hypothesized that the methanogenic archaeon <i>Methanolobus vulcani</i> B1d metabolizes glycine betaine (GB) through a corrinoid-dependent GB:coenzyme M (CoM) methyl transfer pathway. The draft genome sequence of <i>M. vulcani</i> B1d revealed a gene encoding a predicted non-pyrrolysine MttB homolog (MV8460) with high sequence similarity ...[more]
