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Sperm Environmental Epigenetics and Development Study (SEEDS)

ABSTRACT: Infertility is one of the most common reproductive health disorders affecting 16% of couples in the U.S. Most concerning are the new meta-analysis data showing that sperm counts among men in developed countries have declined over 50% in the past four decades. With no sign of reversing this downward trajectory, we may not only be facing a fertility crisis, but low sperm count also has wider public health implications, including increased risks in morbidity and mortality. Given this dramatic decrease in sperm quality over a short period, genetic influences are likely not attributable, but rather, environmental factors encountered over the life-course. The objective of this pilot project is to determine the feasibility of generating metabolomic data from human seminal plasma collected as part of the ongoing SEEDS cohort.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Seminal Plasma

SUBMITTER: Rick Pilsner

PROVIDER: ST002368 | MetabolomicsWorkbench | Thu Nov 17 00:00:00 GMT 2022

REPOSITORIES: MetabolomicsWorkbench

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