Project description:These five raw files represent five technical replicate RPLC data-dependent acquisition analyses of the peptides produced through trypsin digestion and DTT/iodoacetamide reduction/alkylation of an FFPE human colon tumor. The data, collected on a Q-Exactive, offer high resolution for both precursor and fragment ions. Lisa Zimmerman collected these data.
Project description:By using FloChIP’s “sample multiplex” mode, we ChIPed in parallel 5 histone marks (H3K27ac, H3K4me3, H3K4me1 and H3K9me3), going from chromatin to sequencing-ready libraries, in just one day.
Project description:By using FloChIP’s “sample multiplex” mode, we ChIPed in parallel 5 histone marks (H3K27ac, H3K4me3, H3K27me3, H3K4me1 and H3K9me3), going from chromatin to sequencing-ready libraries, in just one day.
Project description:This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/The drug Praziquantel is the most commonly used drug for parasitic flatworms. It is currently being increasingly used in mass drug administration programmes, raising concerns over whether resistance will develop. Although widely used, its mode of action was until very recently uncertain. This study will investigate the praziquantel mode of action and resistance by sequencing the transcriptomes of Dugesia japonica and different stages and strains of S. mansoni.