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Transcriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy

ABSTRACT: Transcriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy

PROVIDER: PRJNA497455 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8077490.fastq.gz	Fastqsanger.gz
	SRR8077500.fastq.gz	Fastqsanger.gz
	SRR8077510.fastq.gz	Fastqsanger.gz
	SRR8077520.fastq.gz	Fastqsanger.gz
	SRR8077530.fastq.gz	Fastqsanger.gz

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Transcriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy

Project description:We report here the transcriptome of sorted enteroendocrine cells from duodenum, ileum and colon from mice after vertical sleeve gastrectomy or sham operation, weight matched or not. We analyze the effect of region of origin and surgery and gene expression and found that only region of origin had an impact on EEC transcriptome

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Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy

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RNAseq Analysis of Mouse Stomach and Intestines Following Vertical Sleeve Gastrectomy

Project description:Bariatric surgery, an effective treatment for obesity and diabetes, leads to profound remodeling of whole body energy homeostasis. We utilized a mouse model of vertical sleeve gastrectomy (VSG), a common bariatric surgery as a tool to identify novel secreted proteins and peptides that might act as important metabolic regulators. We analyzed gene expression in the stomach and intestines following VSG or sham surgery in diet-induced obese mice and sought to identify differentially regulated genes encoding secreted proteins/peptides.

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