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Statins affect gene expression in pancreatic cancer

ABSTRACT: Statins affect gene expression in pancreatic cancer

PROVIDER: PRJNA629289 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11638709.fastq.gz	Fastqsanger.gz
	SRR11638710.fastq.gz	Fastqsanger.gz
	SRR11638711.fastq.gz	Fastqsanger.gz
	SRR11638712.fastq.gz	Fastqsanger.gz
	SRR11638713.fastq.gz	Fastqsanger.gz

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Statins affect gene expression in pancreatic cancer

Project description:The statin family of cholesterol-lowering drugs was shown to influence the risk of multiple types of cancers. However, the anti-tumor effects of statins in pancreatic cancer and their efficacy differs among the individual statins, are not currently well-defined. Thus, the aim of the present study was to identify the biological pathways affected by individual statins in human pancreatic cancer. The study was performed on human pancreatic cancer cell linesMiaPaCa-2 and PANC-1, exposed to three statins (Lovastatin, Fluvastatin and Simvastatin). mRNA-seq were performed (Sequenced with PE150, and 20M reads were generated.)

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