Ontology highlight
ABSTRACT:
REANALYSIS of: PXD000561
OTHER RELATED OMICS DATASETS IN: PXD000561MSV000079514E-PROT-1
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Digestive System
SUBMITTER: Pinto SM, Manda SS, Kim MS, Taylor K, Selvan LD, Balakrishnan L, Subbannayya T, Yan F, Prasad TS, Gowda H, Lee C, Hancock WS, Pandey A
PROVIDER: PAe004856 | PeptideAtlas | 2014-12-31
REPOSITORIES: PeptideAtlas
Alford F P FP Millea M E ME Reaven E P EP Shorenstein R G RG Reaven G M GM
Diabetologia 19750601 3
In order to define the effect of duration of diabetes on hepatic protein sysntesis, membrane-bound and free ribosomes were isolated from livers of rats, 3, 7 and 28 days after administration of intravenous streptozotocin (75 mg/kg). Hepatocytes from the same rats were subjected to ultrastructural quantitative analysis. By day 3 there was a significant loss in the amount of rough endoplasmic reticulum (RER) per volume cytoplasm; however, the normal ratio of membrane-bound ribosomes per unit lengt ...[more]