Dataset Information
Xenopus chromatin proteome survey
Ontology highlight
ABSTRACT:
INSTRUMENT(S): QSTAR XL, instrument model
ORGANISM(S): Xenopus Laevis (african Clawed Frog)
SUBMITTER: 
Guennadi Khoudoli
PROVIDER: PRD000033 | Pride | 2007-10-16
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| PRIDE_Exp_Complete_Ac_3181.xml.gz | Xml |
Items per page: 1 - 1 of 1 |
Publications
The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement.
Cell 20000801 4
At anaphase, the linkage betweeh sister chromatids is dissolved and the separated sisters move toward opposite poles of the spindle. We developed a method to purify metaphase and anaphase chromosomes from frog egg extracts and identified proteins that leave chromosomes at anaphase using a new form of expression screening. This approach identified Xkid, a Xenopus homolog of human Kid (kinesin-like DNA binding protein) as a protein that is degraded in anaphase by ubiquitin-mediated proteolysis. Im ...[more]